SAMe (S-adenosylmethionine), a compound native to the body, is a critical component of many biochemical reactions, including those that affect brain biochemistry and joint health. Numerous studies have indicated that SAMe can help to temporarily alleviate aches and pains resulting from overexertion or stress. A number of well-designed clinical trials show that SAMe may reduce pain and inflammation in the joints, and researchers think it may also promote cartilage repair.
Therefore, SAMe is an all-natural product that can be part of a nutritional program for pain management. In addition, because SAMe is also necessary for the synthesis of neurotransmitters, it plays an important role in the regulation of mood.