Perilla (Perilla frutescens) has been grown widely in Japan, China and Southeast Asia area. The functional compounds of Perilla Seed Extract are flavonoid Aglycons – polyphenols such as Luteolin, Apigenin, Chrysoeriol, and Rosemarinic Acid (which has been reported to support the resistance of redness and swelling).
Though flavonoids normally exist as glycosides in the plant, Perilla Seeds contain Aglycons. It is has been reported that the antioxidative activity and lipoxygenase inhibitory activity of flavonoid Aglycons are stronger than that of corresponding glycosides.
Studies have shown that Perilla Seed polyphenols regulate allergic diseases due to 5-lipoxygenase inhibitory activity and suppression of histamine release from mast cells.
Perilla Seed Extract has anti-bacterial & anti-allergy properties, and can be used in oral care (toothpaste and mouthwash) formulations.